Network-constrained regularization and variable selection for analysis of genomic data

Comment on "network-constrained regularization and variable selection for analysis of genomic data"

MOTIVATION Graphs or networks are common ways of depicting information. In biology in particular, many different biological processes are represented by graphs, such as regulatory networks or metabolic pathways. This kind of a priori information gathered over many years of biomedical research is a useful supplement to the standard numerical genomic data such as microarray gene-expression data. ...

Network-constrained Regularization and Variable Selection for Analysis of Genomic Data

Motivation: Graphs or networks are common ways of depicting information. In biology in particular, many different biological processes are represented by graphs, such as regulatory networks or metabolic pathways. This kind of a priori information gathered over many years of biomedical research is a useful supplement to the standard numerical genomic data such as microarray gene expression data....

Variable selection for multifactorial genomic data

Regularization and variable selection for data with interdependent structures

Variable selection methods are powerful tools in analysis of high dimensional massive data. Specifically, the methods have been applied in gene expression microarray data analysis. It is well known that for genes sharing a common biological pathway or a similar function, the correlations among them can be very high. However, most of the available variable selection methods cannot deal with comp...

analysis of power in the network society

اندیشمندان و صاحب نظران علوم اجتماعی بر این باورند که مرحله تازه ای در تاریخ جوامع بشری اغاز شده است. ویژگیهای این جامعه نو را می توان پدیده هایی از جمله اقتصاد اطلاعاتی جهانی ، هندسه متغیر شبکه ای، فرهنگ مجاز واقعی ، توسعه حیرت انگیز فناوری های دیجیتال، خدمات پیوسته و نیز فشردگی زمان و مکان برشمرد. از سوی دیگر قدرت به عنوان موضوع اصلی علم سیاست جایگاه مهمی در روابط انسانی دارد، قدرت و بازتولید...